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Dr Lisi Flores Aguilar
Name:
Dr Lisi Flores Aguilar
Job Title:
Postdoctoral Researcher
Place of work / study:
University of California, Irvine
Area of Research:
Alzheimer’s disease & Down syndrome
How is your research funded:
Various
Tell us a little about yourself:
I have an extensive background and research expertise in the pathological molecular mechanisms occurring at the preclinical stages of Alzheimer’s disease (AD). Specifically, I have focused on the early contribution of the immune system to AD preclinical stages.
During my graduate studies, I investigated neuroinflammatory changes occurring before the appearance of cognitive symptoms in Down syndrome (DS) and the general population. My research findings were published in recognized neuroscience journals. My contribution to DS research was highlighted as a top publication by the journal Brain and Free Neuropathology. Further, I have received several academic and presentation awards, including the Brain Star Award from the Canadian Institutes of Health Research.
While at McGill, I also created a unique DS post-mortem brain collection at McGill University. Complementing my research skills, I supervised and mentored undergraduate and graduate students, acted as a reviewer of scientific manuscripts, and successfully delivered scientific presentations at national and international scientific conferences.
After finishing my Ph.D, I joined Altasciences as a Bioanalytical Principal Investigator. This experience enriched my knowledge about reliable biomarker assessment in biofluids, a solid asset for my future studies.
At UCI, I am currently researching cerebrovascular pathology in people with Down syndrome and Alzheimer’s disease under the mentorship of Dr. Elizabeth Head.
Tell us a fun fact about yourself:
I love dogs and myself have a golden retriever
Why did you choose to work in dementia research?
Down syndrome and dementia are closely connected in medical research. Individuals with Down syndrome have a higher likelihood of developing Alzheimer’s disease, a common form of dementia, as they age. Understanding the connection between Down syndrome and dementia is crucial for early intervention and support. It also underscores the importance of regular health assessments for individuals with Down syndrome as they age.
What single piece of advice would you give to an early career researcher?
Keep up-to-date with the latest research and developments in your field. Attend workshops, subscribe to relevant journals, and being active in professional organisations such as ISTAART can help you stay at the forefront of your field.
Dr Clíona Farrell
