This playlist contains recordings made at the PREVENT Study 10 year Anniversary Celebration Event held on the on 23rd March 2024 at the De Vere Grand Connaught Rooms, London. The event brought together participants, researchers and a wide range of stakeholders to talk about the programme, its progress, discoveries and the future.
Dementia Researcher recorded the event through our Open Access Events initative if you’re an event organisers, get in touch to see how we could support your event.
PREVENT is a multi-centre prospective cohort study in the UK and Ireland that aims to examine mid-life risk factors for dementia, identify and describe the earliest indices of disease development.
For more information on PREVENT Dementia visit: https://preventdementia.co.uk/
This talk features Katherine Gray, Alzheimer’s Society’s Head of Research.
Katherine opened the event, and expressed pride in project, it’s discoveries and the Alzheimer Society's support of the Prevent programme, a long-term, large-scale research project aimed at combating dementia. Katherine shares news that Alzheimer’s Society has funded a wide range of research projects for over 30 years, investing £12.2 million in the last financial year alone.
Katherine emphasises the importance of including the voices of those affected by dementia in the Society's research and funding decisions.
This recording was made at the PREVENT Study 10 year Anniversary Celebration Event held on the
on 23rd March 2024 at the De Vere Grand Connaught Rooms, London. The event brought together participants, researchers and a wide range of stakeholders to talk about the programme, its progress, discoveries and the future.
PREVENT is a multi-centre prospective cohort study in the UK and Ireland that aims to examine mid-life risk factors for dementia, identify and describe the earliest indices of disease development.
For more information on PREVENT Dementia visit:
https://preventdementia.co.uk/
Dementia Researcher works alongside events organisers to share their work. If you're organising a dementia research event and would like us to record or share your talks, to get them open access and to reach a wider audience, get in touch:
https://www.dementiaresearcher.nihr.ac.uk
Follow us on Social Media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
#PreventDementia #DementiaResearch #Dementia #TraumaticBrainInjury #TBI #Neuroimaging @alzheimerssociety
0
YouTube Video UExlVUkxR0hCNEV2UWZFQUN3ZndlbVNlZVIwdGUteGo2by4wMTcyMDhGQUE4NTIzM0Y5
Katherine Gray - Prevent Dementia Study Anniversary Event Introduction
Dementia Researcher
22/04/2024 9:55 am
This talk features Craig Ritchie, Professor of Medicine at University of St Andrews and Chief Executive Officer of Scottish Brain Sciences.
In this presentation Professor Ritchie discusses the progress of the Prevent Dementia Programme over the past decade. With initial funding from the Alzheimer's Society, the programme has recruited 802 participants, conducted over 1,500 study visits, and produced over 50 publications. Craig highlights the importance of the programme in advancing understanding of Alzheimer's disease and dementia, and its role in influencing policy and practice. He finishes his talk with seven predictions for the next decade, including the development of new therapies, early detection methods, and a greater understanding of the impact of contact sports on brain health.
This recording was made at the PREVENT Study 10 year Anniversary Celebration Event held on the on 23rd March 2024 at the De Vere Grand Connaught Rooms, London. The event brought together participants, researchers and a wide range of stakeholders to talk about the programme, its progress, discoveries and the future.
PREVENT is a multi-centre prospective cohort study in the UK and Ireland that aims to examine mid-life risk factors for dementia, identify and describe the earliest indices of disease development.
For more information on PREVENT Dementia visit:
https://preventdementia.co.uk/
Dementia Researcher works alongside events organisers to share their work. If you're organising a dementia research event and would like us to record or share your talks, to get them open access and to reach a wider audience, get in touch:
https://www.dementiaresearcher.nihr.ac.uk
Follow us on Social Media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
#PreventDementia #DementiaResearch #Dementia #TraumaticBrainInjury #TBI #Neuroimagine
3
YouTube Video UExlVUkxR0hCNEV2UWZFQUN3ZndlbVNlZVIwdGUteGo2by41NkI0NEY2RDEwNTU3Q0M2
Professor Craig Ritchie - Prevent Dementia Study the story so far
Dementia Researcher
22/04/2024 9:55 am
This talk features John O’Brien, Professor of Old Age Psychiatry at University of Cambridge.
Professor O’Brien discusses the findings of the neuroimaging element of the Prevent Study. The study found that midlife is a crucial time for potential changes in the brain, with the goal of identifying structural or functional changes in those at risk of future dementia. The study also examined how these changes relate to inherited factors like genes and age, as well as environmental or acquired risk factors such as smoking, high blood pressure, and raised cholesterol.
The study found that brains of people at risk of future dementia are generally well-preserved, with subtle changes starting to appear in some areas. The main effect on brain health was found to be modifiable risk factors, rather than genetic ones. The study suggests that maintaining vascular health and leading a healthy lifestyle can help preserve brain health.
This recording was made at the PREVENT Study 10 year Anniversary Celebration Event held on the on 23rd March 2024 at the De Vere Grand Connaught Rooms, London. The event brought together participants, researchers and a wide range of stakeholders to talk about the programme, its progress, discoveries and the future.
PREVENT is a multi-centre prospective cohort study in the UK and Ireland that aims to examine mid-life risk factors for dementia, identify and describe the earliest indices of disease development.
For more information on PREVENT Dementia visit:
https://preventdementia.co.uk/
Dementia Researcher works alongside events organisers to share their work. If you're organising a dementia research event and would like us to record or share your talks, to get them open access and to reach a wider audience, get in touch:
https://www.dementiaresearcher.nihr.ac.uk
Follow us on Social Media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
#PreventDementia #DementiaResearch #Dementia #TraumaticBrainInjury #TBI #Neuroimaging
2
YouTube Video UExlVUkxR0hCNEV2UWZFQUN3ZndlbVNlZVIwdGUteGo2by4yODlGNEE0NkRGMEEzMEQy
Professor John O'Brien - Prevent Dementia Study, Imaging Overview
Dementia Researcher
22/04/2024 9:55 am
This talk features Professor Willie Stewart, Consultant Neuropathologist at the Queen Elizabeth University Hospital, Glasgow, and honorary Associate Professor status at the University of Glasgow. Additionally he is joined by special guests Gill Burns, MBE former rugby union player who represented England between 1988 and 2002, and Jason White, Ex Scotland international rugby player.
Professor Stewart discusses his research into brain injuries in sports, particularly rugby and football, and their potential long-term effects on brain health. He explains that for over a century, it has been known that boxers may develop lifelong brain health problems from participating in the sport. However, it was only about 20 years ago that a similar pathology was found in a former American football player, leading to the recognition that this could be a problem for wider sports and exposures to brain injury. Willie’s research has found that the risk of a former footballer dying with a dementia syndrome is about three and a half times higher than expected. He also discusses the introduction of rugby and football cohorts into the prevent dementia programme and the ongoing analysis of data from these groups.
After his presentation Willie is joined by Jason White and Gill Burns, two former international Rugby players who talk about their experiences working with prevent, and how their sports impacted them and their brain health.
This recording was made at the PREVENT Study 10 year Anniversary Celebration Event held on the on 23rd March 2024 at the De Vere Grand Connaught Rooms, London. The event brought together participants, researchers and a wide range of stakeholders to talk about the programme, its progress, discoveries and the future.
PREVENT is a multi-centre prospective cohort study in the UK and Ireland that aims to examine mid-life risk factors for dementia, identify and describe the earliest indices of disease development.
For more information on PREVENT Dementia visit:
https://preventdementia.co.uk/
Dementia Researcher works alongside events organisers to share their work. If you're organising a dementia research event and would like us to record or share your talks, to get them open access and to reach a wider audience, get in touch:
https://www.dementiaresearcher.nihr.ac.uk
Follow us on Social Media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
#PreventDementia #DementiaResearch #Dementia #TraumaticBrainInjury #TBI #Neuroimaging #brainhealth #Sportsbraininjury
2
YouTube Video UExlVUkxR0hCNEV2UWZFQUN3ZndlbVNlZVIwdGUteGo2by41MzJCQjBCNDIyRkJDN0VD
Professor Willie Stewart & Guests - Prevent Dementia Study, Rugby & Football Cohorts
Dementia Researcher
22/04/2024 9:55 am
This talk features Lorina Naci, Associate Professor, leader of the 'Consciousness and Cognition' group, and Fellow of Trinity College Dublin.
Professor Naci discusses the findings of her Prevent Study research, which aimed to understand the early signs of these dementia diseases. The research found that participants with a parent who has dementia have poorer visual memory, and those with a high dementia score have greater difficulty recalling names associated with faces. The study also found that engaging in stimulating activities, such as socialising, playing a musical instrument, and physical activity, can help build cognitive reserve and maintain cognition. Furthermore, higher occupational attainment was found to be associated with stronger cognition in females, especially those with a genetic risk for Alzheimer's disease.
This recording was made at the PREVENT Study 10 year Anniversary Celebration Event held on the on 23rd March 2024 at the De Vere Grand Connaught Rooms, London. The event brought together participants, researchers and a wide range of stakeholders to talk about the programme, its progress, discoveries and the future.
PREVENT is a multi-centre prospective cohort study in the UK and Ireland that aims to examine mid-life risk factors for dementia, identify and describe the earliest indices of disease development.
For more information on PREVENT Dementia visit:
https://preventdementia.co.uk/
Dementia Researcher works alongside events organisers to share their work. If you're organising a dementia research event and would like us to record or share your talks, to get them open access and to reach a wider audience, get in touch:
https://www.dementiaresearcher.nihr.ac.uk
Follow us on Social Media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
#PreventDementia #DementiaResearch #Dementia #TraumaticBrainInjury #TBI #Neuroimaging
1
YouTube Video UExlVUkxR0hCNEV2UWZFQUN3ZndlbVNlZVIwdGUteGo2by4wOTA3OTZBNzVEMTUzOTMy
Dr Lorina Naci - Prevent Dementia Study, Cognition & Lifestyle Findings
Dementia Researcher
22/04/2024 9:54 am
This talk features Dr Laura Booi, Senior Research Fellow at Leeds Beckett University.
The Next Generation Brain Health (NextGen) programme of research is co-lead by Drs Laura Booi and Francesca Farina. The project aims to identify what young adults know about what is good and bad for their brain health, and what they are unsure of. The team found that there is a lack of knowledge about risk factors for dementia in young adults and those under the age of 40, with early education being the only known variable that can reduce the risk of dementia later in life. The project conducted focus groups with young adults, asking them about their perceptions of brain health. The team found that young adults had many questions about how various factors, such as birth control, stress, and cannabis, affect their brain health. The project is now focusing on conducting focus groups with higher risk populations, such as young adults who play contact sports and those with obesity.
The NextGen team developed has also developed a global survey on brain health in young adults, aiming to get 5,000 responses. The survey includes questions about awareness of dementia and brain health, self-reported understanding of risk factors, barriers to brain health, and attitudes towards genetic testing.
The Survey is still accepting responses in some parts of the world (as of 29th March 2024):
https://bit.ly/nextgenbrain
This recording was made at the PREVENT Study 10 year Anniversary Celebration Event held on the on 23rd March 2024 at the De Vere Grand Connaught Rooms, London. The event brought together participants, researchers and a wide range of stakeholders to talk about the programme, its progress, discoveries and the future.
PREVENT is a multi-centre prospective cohort study in the UK and Ireland that aims to examine mid-life risk factors for dementia, identify and describe the earliest indices of disease development.
For more information on PREVENT Dementia visit:
https://preventdementia.co.uk/
Dementia Researcher works alongside events organisers to share their work. If you're organising a dementia research event and would like us to record or share your talks, to get them open access and to reach a wider audience, get in touch:
https://www.dementiaresearcher.nihr.ac.uk
Follow us on Social Media:
https://www.instagram.com/dementia_researcher/
https://www.facebook.com/Dementia.Researcher/
https://twitter.com/demrescommunity
https://www.linkedin.com/company/dementia-researcher
#PreventDementia #DementiaResearch #Dementia #TraumaticBrainInjury #TBI #Neuroimaging
2
YouTube Video UExlVUkxR0hCNEV2UWZFQUN3ZndlbVNlZVIwdGUteGo2by5DQUNERDQ2NkIzRUQxNTY1
Dr Laura Booi - Next Generation Brain Health Study
Dementia Researcher
22/04/2024 9:54 am
Full videos with captions are available on our YouTube Channel.
About the Speakers
Katherine Gray, is Head of Research at Alzheimer’s Society. Her work involves leading a team to support delivery of research grants, setting research strategy and work to support early career researchers working in all areas of discovery.
Craig Ritchie, Professor of Medicine at University of St Andrews and Chief Executive Officer of Scottish Brain Sciences. Craig graduated from Aberdeen Medical School in 1991, gained a Masters in Epidemiology in 2002, and a PhD in Mental Health from University College London in 2006. His interests lie in translational epidemiology and clinical trials for the secondary prevention of dementia. His work in this field dates back to 1997 when he worked in the laboratory of Prof Colin Masters in the University of Melbourne before returning to UCL in 2000 to complete his PhD through an MRC Health Services Research Fellowship.
John O’Brien, Professor of Old Age Psychiatry at University of Cambridge. John leads the Old Age Psychiatry Research Group which is part of the Department of Psychiatry at the University of Cambridge. His own research focusses on the study of dementia, especially Lewy body dementia, and uses a number of methodologies to try to improve the diagnosis and management of these disorders. In particular, utilising multi-modal imaging with MRI, MEG and novel PET and fluid markers to study pathophysiological processes and develop biomarkers for diagnosis and disease progression, and conduct clinical trials to improve patient management.
Willie Stewart, Professor of Neuropathology, University of Glasgow. Willie is a consultant neuropathologist and a leading expert in brain injury in sport. He published the famous FIELD study in 2019, which demonstrated that professional footballers are 5 times more likely to suffer from dementia than the normal population. His influential work has triggered football authorities across the world to listen to these serious health risks and his ongoing work has ignited change. He is currently running the Sports element of the Prevent Study and BrainHOPE study, jointly funded by the FA and FIFA, to gather more information on players and their risks, and, importantly, to identify possible ways to reduce the risk of developing dementia in former professional footballers who have already been exposed to significant numbers of head impacts.
Gill Burns, MBE is a former rugby union player who represented England between 1988 and 2002, including when they won the 1994 Women’s Rugby World Cup. She also captained her country between 1994 and 1999. She was selected for England only one year after first playing rugby union. She went on to play in four World Cups, including the inaugural Women’s Rugby World Cup – hosted by Wales in 1991. Gill is passionate about brain health and After retiring as a player, Burns was appointed President of the Rugby Football Union for Women.
Jason White, is a Scottish former rugby union footballer. He was a utility forward who played in the second or back row of the scrum – lock, flanker, or number eight. White played at club level for Glasgow Caledonians (now known as Glasgow Warriors); the French Top 14 side ASM Clermont Auvergne; and English Premiership side Sale Sharks. He won 77 caps playing for Scotland, captaining the side on 19 occasions. Jason is an important figure in discussing the importance of tbi and concussion in sports and their connection to neurodegenerative diseases.
Dr Lorina Naci, Associate Professor, leader of the ‘Consciousness and Cognition’ group, and Fellow of Trinity College Dublin. Lorina leads the ‘Consciousness and Cognition’ group (www.lorinanaci.org). She received her PhD from the University of Cambridge as an International Cooke Fellow. Her work focuses on developing novel biomarkers of healthy and disordered cognition in brain-injured and ageing populations, including individuals with early Alzheimer’s dementia.
Dr Laura Booi, Senior Research Fellow at Leeds Beckett University. Laura is a social gerontologist focused on research and advocacy relating to brain health equity and dementia, globally and locally. Laura is leading efforts to build inclusive communities through co-producing research with people living with dementia and developing social entrepreneurial ventures to connect and support dementia-focused leaders. Additionally Laura is leading a sub-study within PREVENT the large-scale, multicentre study which will provide insight into how dementia prevention research can be more inclusive to seldom heard populations
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Dr Lis Grey
NIHR