Research Fellow: Hippocampal-entorhinal neural networks

The Krupic Lab in the UKDRI at University College London is seeking a Research Fellow to investigate the role of disrupted deep brain circuitry in diminished spatial memory function in Alzheimer’s

The UK Dementia Research Institute (UK DRI) is the biggest UK initiative supporting research to fill the major knowledge gap in our basic understanding of the diseases that cause dementia.

Research from UK DRI at UCL covers the journey from the patient to the laboratory and back to the patient with improved diagnosis, biomarkers and candidate therapies put to the test.

The Krupic Lab at the UK DRI at UCL aims to understand how accumulation of Tau and amyloid-beta pathology affects hippocampal-entorhinal neural networks and cognitive functions in age-related neurodegenerative diseases such as Alzheimer’s disease using cutting edge neural recording techniques, state of the art behaviour techniques, and computational approaches.

About the role

We are now recruiting a highly motivated, experienced, and self-driven Research Fellow to join the Krupic Lab to help investigate the role of disrupted deep brain circuitry in diminished spatial memory function in Alzheimer’s disease. The research will focus on both healthy and Alzheimer’s disease related interactions modelled by accumulation of amyloid-beta and Tau proteins. One of your main tasks will be to help implement the long-term neural recordings using smart Kages.

The post is available from 15 January 2025 and is funded by the UK DRI until 31 May 2025 in the first instance, with possibility of extension.

For a full job description and to apply for this role please visit UCL’s online recruitment portal (https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs) and search using vacancy reference B02-08079.

About you

You will have a PhD degree in Neuroscience and experience in in vivo recordings in behaving mice. You should also have a good background in complex datasets analysis using MATLAB and/or Python programming languages, and a proven track record of publications, presentations, and research skills. Extensive laboratory experience in an interdisciplinary research environment studying immunology, neuroimmunology, glial biology and/or neuroscience is also required for the role, as is the ability to execute a programme of experiments through the design and improvement phase to data curation and publication.

What we offer

Appointment as Research Fellow is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be as Research Assistant (salary £38,357 – £41,005 per annum) with appointment as Research Fellow being backdated to the date of final submission of the PhD thesis.

As well as the exciting opportunities this role presents, we also offer great benefits; visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.

We will consider applications to work on a part-time, flexible, and job share basis wherever possible.

This appointment is subject to UCL Terms and Conditions of Service for Research and Professional Services Staff. Please visit https://www.ucl.ac.uk/human-resources/conditions-service-research-teaching-and-professional-services-staff for more information.

Our commitment to Equality, Diversity and Inclusion

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. 12% of Institute staff are actively working on EDI initiatives; visit https://www.ucl.ac.uk/ion/equality-diversity-inclusion for more information about what we’re doing. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce; these include people from Black, Asian and ethnic minority backgrounds, disabled people, LGBTQI+ and gender diverse people in all roles, and women in Grade 9 and 10 roles.