PhD: Multiomics Scores for Predicting Age of Onset in ALS

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Website KingsCollegeLon King's College London

Closing date: 30th January

bluesky@kingscollegelondon.bsky.social

 

Funded PhD with Dr Ahmad  Al Khleifat exploring PrognostiOmics: Multiomics Scores for Predicting Age of Onset in ALS


Amyotrophic lateral sclerosis (ALS) affects individuals at varying ages, yet the reasons remain unknown. Our primary aim is to identify genomic factors underlying the diverse age of disease onset in ALS, ultimately leading to the development of a biomarker. Our research delves deep into ALS genetics, focusing on genomic variations that may influence the timing of disease onset. With this knowledge, we seek to create a biomarker capable of predicting when ALS may occur.   This project’s significance lies in addressing the current uncertainty about when to initiate ALS treatment. Identifying the timing of disease onset will guide treatment decisions, potentially leading to more effective interventions. Our study will not only enhance our understanding of disease progression but also uncover new genetic factors linked to disease timing. These findings may offer insights into early detection and intervention for individuals at risk of ALS, ultimately improving patient outcomes.

We are now accepting applications for 1 October 2025

How to apply

Candidates should possess or be expected to achieve a 1st or upper 2nd class degree in a relevant subject including the biosciences, computer science, mathematics, statistics, data science, chemistry, physics, and be enthusiastic about combining their expertise with other disciplines in the field of healthcare.

Important information for International Students:

It is the responsibility of the student to apply for their Student Visa. Please note that the EPSRC DRIVE-Health studentship does not cover the visa application fees or the Immigration Health Surcharge (IHS) required for access to the National Health Service. The IHS is mandatory for anyone entering the UK on a Student Visa and is currently £776 per year for each year of study. Further detail can be found under the International Students tab below.

Funding

Enhanced Studentships to Attract Top Talent

Each studentship is fully funded for 4 years.

This includes tuition fees, a stipend and a generous allowance for project consumables.

Tuition Fees: these will be covered for both Home and International students.

Stipend: students will receive a tax-free living allowance of £23,814 per year (current projection for Academic Year 2025/26).

Research Training Support Grant (RTSG): up to £20,000 over 4 years for research consumables and attending national and international conferences.

Next Steps

  1. Applications submitted by the closing date of Thursday 30 January 2025 will be considered by the CDT. We will contact shortlisted applicants with information about this part of the recruitment process.
  2. Candidates will be invited to attend an interview. Interviews are projected to take place in March 2025.
  3. Project selection will be through a panel interview chaired by either Professor Richard Dobson and Professor Vasa Curcin (CDT Directors) followed by informal discussion with prospective supervisors.
  4. If you have any questions related to the specific project you are applying for, please contact the main supervisor of the project directly.

For any other questions about the recruitment process, please email us at

 drive-health-cdt@kcl.ac.uk.

To apply for this job please visit www.drive-health.org.uk.

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