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Technology advancements for neuropathology diagnostics and research
June 11 - June 13
Advancements in novel technologies over the last decade and their implementation in neuroscience have significantly accelerated neuroscience research and the development of diagnostic tools in neuropathology. Many of these technologies have transformed the capabilities of a neuroscientist and neuropathologist in the 21st century.
In this summer school, the audience will have the opportunity to learn about novel technologies paving the way for innovative neuroscience research and how these tools and approaches are implemented in diagnostic practice and study for a range of neurological diseases.
During the summer school, experts in the corresponding field will explain each tool’s scientific principles, followed by an overview of the potential utility, with examples of application in research and diagnostics of neurodegenerative diseases and neurooncology.
Agenda
13:00 – 13:30 – 11/06/2024: WELCOME AND INTRODUCTION
Zane Jaunmuktane, BNS summer school organiser
13:30 – 15:30 – 11/06/2024: TECHNOLOGIES IN GENOMICS AND EPIGENETICS
Genome sequencing in neurodegeneration
Ariana Tucci, London, United Kingdom
Genome sequencing on liquid biopsies in neurooncology
Kendra K Maass, Heidelberg, Germany
Epigenetics in neurodegeneration
Conceicao Bettencourt, London, United Kingdom
16:00 – 18:00 – 11/06/2024: SINGLE CELL AND SINGLE MOLECULE GENETIC ANALYSIS
Nanopore sequencing in neurooncology practice
Areeba Patel, Heidelberg, Germany
Nanopore sequencing of long read DNA and RNA for study of neurodegeneration
Emil Gustavsson, London, United Kingdom
Single cell DNA analysis in neurodegeneration
Christos Proukakis, London, United Kingdom
09:30 – 11:00 – 12/06/2024: GENE EXPRESSION ANALYSIS
Spatial transcriptomics applications to study neurodegenerative diseases
Anna Mallach, London, United Kingdom
Bulk RNA seq and deconvolution for cell identification in neurooncology
Thomas Stone, London, United Kingdom
11:00 – 13:00 – 12/06/2024: TECHNOLOGIES IN PROTEIN BIOLOGY
Seeding aggregation assays for misfolded protein detection
Alessia Santambrogio, Cambridge, United Kingdom
Nanopore technology application for protein variant detection
Henry Brinkerhoff, Seattle, USA
AI-based software development for protein structure prediction
Milot Mirdita, Seoul, South Korea
15:00 – 18:00 – 12/06/2024: ADVANCED IMAGING AND DATA PROCESSING TECHNOLOGIES
Super-resolution microscopy for high spatial precision imaging
Steve Lee, Cambridge, United Kingdom
CryoEM application for protein filament structure identification
Yang Yang, Cambridge, United Kingdom
Correlative light and electron microscopy (CLEM)
Minee Choi, Daejeon, South Korea
09:30 – 12:00 – 13/06/2024: ADVANCED IMAGING AND DATA PROCESSING TECHNOLOGIES
Multiplex ion beam imaging by time of flight (MIBI-TOF) mass spectrometry
Sean Curtis Bendall, Stanford University, USA
AI and machine learning-based applications in neurooncology
Katherine Hewitt, Aachen, Germany
Data-driven modelling of neurodegenerative disease progression
Alexandra Young, London, United Kingdom
