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Improving animal models for the study of Alzheimer’
23/03/2023 @ 2:00 pm - 3:00 pm
The UK DRI is delighted to welcome Dr Michael Sasner (The Jackson Laboratory, Bar Harbor, ME, USA) for a special webinar to discuss recent advances in efforts to generate translationally-relevant mouse models of Alzheimer’s disease.
Dr Sasner’s talk will focus on recent research highlights from MODEL-AD (Model Organism Development & Evaluation for Late-Onset Alzheimer’s Disease), other reporter models for the study of microglial and astrocytic substates, models to study the role of APOE in AD risk and will also cover other ongoing projects to create more translationally relevant mouse models of familial AD.
The MODEL-AD program aims to generate new animal models of late-onset AD based on human genetic variants; characterise models in a standardized and rigorous manner; align pathophysiological features with corresponding states of clinical disease using translatable biomarkers; establish guidelines for preclinical testing in animal models; and make all models, protocols, and validation data available without restriction. Funded by the National Institute of Ageing (USA), the consortium includes members from the Indiana University School of Medicine, The Jackson Laboratory, Sage Bionetworks, the University of Pittsburgh School of Medicine and the University of California, Irvine.
➡️ This event is open to both UK DRI and external researchers.
⏰ The seminar is scheduled for 1 hour, starting at 2pm GMT.
