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Engineering iPSCs to Model Neurological Diseases
May 6 - May 8
We invite you to join us for a one-day symposium, followed by a 4 day hands-on workshop, focused on the genome editing and use of induced pluripotent stem cells (iPSC).
The 1-day symposium will be held on May 6, in a hybrid format, and highlights new technologies for genome editing featuring key leaders in the field. The 4-day, in-person, lab-based workshop will provide participants with state-of-the-art knowledge of iPSC disease modeling along with training in associated methods. The workshop will be held May 7-10 and will have limited capacity in order to provide personal support for the training.
Induced pluripotent stem cells (iPSC) have been used to model many human genetic conditions. iPSCs can be edited to replicate human genetic variants at endogenous levels and can then be differentiated into target cell types, including human brain cells that are difficult to study in vivo. Leveraging expertise, tools and methodologies developed in part through the iPSC neurodegenerative disease initiative (iNDI), we invite you to a one day symposium with thought leaders in the iPSC field that will allow participants to learn and discuss leading edge applications of these techniques. The symposium will be led by the co-directors of the Center for Alzheimer’s and Related Dementias’ iNDI project, Dr. Mark Cookson (Chief of the Laboratory of Neurogenetics, NIA) and Dr. Michael Ward (Chief of the Inherited Neurodegenerative Diseases Section, NINDS). A virtual option for the symposium is available for those that cannot attend in person.
The symposium will be followed by a 4-day in-person workshop that will provide a small cohort of participants with a practical understanding of the methods for utilization of iPSC resources, including hands-on experience in SNV editing, knockout , and Halo tagging of genes. The workshop will be led by Prof. Bill Skarnes, a recognized leader in stem cell genome engineering and Director of Cellular Engineering at Jackson Laboratory for Genomic Medicine, in collaboration with the directors of the iNDI project, Dr. Mark Cookson (Chief of the Laboratory of Neurogenetics, NIA) and Dr. Michael Ward (Chief of the Inherited Neurodegenerative Diseases Section, NINDS).
Workshop Registrations has closed.
Symposium Registration Deadline: April 22 (in-person) or May 5 (virtual)
Sponsored by the Chan-Zuckerberg Initiative (CZI) and by The Jackson Laboratory
