Introducing: iPSC Collection from Tauopathy Patients
A multi-institutional group, including members of the Tau Consortium, unveiled a stem cell tool kit for scientists studying primary tauopathies.
All posts by Alz Forum
MRI and Machine Learning Depict Brain Aging in Health, Disease
The human brain follows a typical ageing trajectory, but diseased brains are further along, according to a paper in the September 24 Nature Neuroscience.
In Alzheimer’s, More TREM2 Is Good for You
Certain mutations in TREM2 strongly increase risk for late-onset Alzheimer’s. Could tweaking the function of this microglial receptor help people with the disease?
Human Microglia Make Themselves at Home in Mouse Brain
As microglia become more central to Alzheimer’s research, researchers are seeking better model systems to study their in vivo behavior – can chimeric mice provide a solution?
Physical Activity May Shield the Brain from the Onslaught of Aβ
Physical activity not only benefits the heart and the body, it may also shield the brain from the damaging effects of Aβ says study published in JAMA Neurology (July 16)
Drawing Closer: Alzheimer’s Blood Test for Primary Care
In today’s JAMA Neurology, researchers led by Oskar Hansson, Lund University, Sweden, report how a fully automated immunoassay for plasma Aβ performed when they put it through its paces.
Brain Conference Spotlights Transcriptomics, Therapeutic Strategies
Around 140 scientists gathered in Rungstedgaard, north of Copenhagen, Denmark, May 5–9 for the biannual Brain Conference organised by the Federation of European Neuroscience Societies and the Lundbeck Foundation. This article from the Alz Forum shares news from the event.
Resetting Brain Rhythms Gives Working Memory a Brief Boost
Groups of neurons fire in sync with each other across the brain when it performs a task; however, with age, they fall out of step. Can an electrical current have a restorative effect?
Multi-Gene Score Predicts Cognitive Decline Independently of Brain Imaging
On their own, most genetic variations linked to Alzheimer’s disease affect a person’s risk by a minuscule amount. Together, however, they pack a wallop, This article from Alz Forum explains.
Cancer Treatment Takes Aim at Tauopathy
3 years ago Michal Schwartz at the Weizmann Institute of Science, deployed an immune-boosting approach pioneered for cancer in a mouse model of Alzheimer’s disease. How has this progressed?
An Antimicrobial Approach to Treating Alzheimer’s?
Brush, Floss, Take a Protease Inhibitor? Do periodontal bacteria cause some cases of Alzheimer’s disease? Scientists at one start-up think so.
Neurofilament in Blood Foretells Early Onset Alzheimer’s
A paper published online on the 21st January in Nature Medicine finds that in familial Alzheimer’s disease, blood levels of neurofilament light (NfL) rise 16 years before the predicted age…